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Description:Health risks[ edit ] Central obesity is associated with a statistically higher risk of heart disease , hypertension , insulin resistance , and Diabetes Mellitus Type 2 see below. Central obesity is a symptom of Cushing's syndrome  and is also common in patients with polycystic ovary syndrome PCOS. Central obesity is associated with glucose intolerance and dyslipidemia. Once dyslipidemia becomes a severe problem, an individual's abdominal cavity would generate elevated free fatty acid flux to the liver. The effect of abdominal adiposity occurs not just in those who are obese, but also affects people who are non-obese and it also contributes to insulin sensitivity.